If they are in a group of friends, you can include the friends in conversations or as assistants, and talk ABOUT the heckler but not directly to them. Quickly, they will quieten down or start arguing with their friends, and not be directed at you the whole time.
Don't insult them or antogonise them directly. Be nice to them, constantly belittle yourself and agree with every disparaging comment and let the rest of the crowd manage them, and pump you up.
Often, I like to tell the crowd a loud 'secret'. It's ok, he's actually my wife dressed up, like the opposite of Mrs Doubtfire. She's here to stop me flirting...
Lot's of different ways to handle them...
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